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KMID : 0985520150200040222
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Korean Journal of Pancreas and Biliary Tract
2015 Volume.20 No. 4 p.222 ~ p.227
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Acute Necrotizing Pancreatitis during L-asparaginase Treatment in a Patient with Acute Lymphoblastic Leukemia
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이지애:Lee Ji-Ae
김효정:Kim Hyo-Jung/김재선:Kim Jae-Seon/이정민:Lee Jung-Min/김지은:Kim Ji-Eun/임상윤:Lim Sang-Youn/김성민:Kim Seong-Min/이연호:Lee Yeon-Ho
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Abstract
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L-asparaginase is an important component of antileukemic therapy in patients with acute lymphoblastic leukemia. The degree of L-asparaginase toxicity is variable. Several cases of L-asparaginase related pancreatitis have been reported in the literature. However, necrotizing pancreatitis in adult has not been reported yet. Herein, we present a case of necrotizing pancreatitis caused by L-asparaginase that was complicated by pancreatic duct leakage and pseudocyst formation, but successfully treated with percutaneous drainage and octreotide treatment.
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KEYWORD
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L-asparaginase, Acute lymphoblastic leukemia, Acute pancreatitis, Pseudocyst, Pancreatic duct leak
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